BDBM50212135 CHEMBL266017::N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-1-cyclopropyl-3-[(1S,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]cyclopentane-1-carboxamide

SMILES C[C@H]1CN(CC[C@]11C=Cc2ccccc12)C1CCC(C1)(C1CC1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=PVVAQUKXSCGSNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212135   

TargetC-C chemokine receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212135(N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-1-cyclo...)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212135(N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-1-cyclo...)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed