BDBM50212043 4-phenyl-2-(4-(pyrrolidin-1-ylmethyl)phenylamino)pyrimidine-5-carbonitrile::CHEMBL233454

SMILES N#Cc1cnc(Nc2ccc(CN3CCCC3)cc2)nc1-c1ccccc1

InChI Key InChIKey=NXZAMNSWBHNALK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212043   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212043(4-phenyl-2-(4-(pyrrolidin-1-ylmethyl)phenylamino)p...)
Affinity DataIC50: 61nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212043(4-phenyl-2-(4-(pyrrolidin-1-ylmethyl)phenylamino)p...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed