BDBM50212042 2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-2-yl)pyrimidine-5-carbonitrile::CHEMBL390186

SMILES OCCc1ccc(Nc2ncc(C#N)c(n2)-c2cc3ccccc3[nH]2)cc1

InChI Key InChIKey=UPTXKZNTICNNEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212042   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212042(2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-2-yl...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212042(2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-2-yl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed