BDBM50212036 2-(3-methoxy-4-(pyrrolidin-1-ylmethyl)phenylamino)-4-phenylpyrimidine-5-carbonitrile::CHEMBL387829

SMILES COc1cc(Nc2ncc(C#N)c(n2)-c2ccccc2)ccc1CN1CCCC1

InChI Key InChIKey=QJDIDSFWZZTQFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212036   

TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212036(2-(3-methoxy-4-(pyrrolidin-1-ylmethyl)phenylamino)...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212036(2-(3-methoxy-4-(pyrrolidin-1-ylmethyl)phenylamino)...)
Affinity DataIC50: 91nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed