BDBM50212033 4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenylamino)pyrimidine-5-carbonitrile::CHEMBL394577

SMILES CN1CCN(CCc2ccc(Nc3ncc(C#N)c(n3)-c3ccc(cc3)C(C)(C)N)cc2)CC1

InChI Key InChIKey=LNPGEMWHMALOTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212033   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212033(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(4-methyl...)
Affinity DataIC50: 21nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212033(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(4-methyl...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed