BDBM50212032 2-(2-methyl-1H-indol-5-ylamino)-4-phenylpyrimidine-5-carbonitrile::CHEMBL233669

SMILES Cc1cc2cc(Nc3ncc(C#N)c(n3)-c3ccccc3)ccc2[nH]1

InChI Key InChIKey=VFUORJNEIXHWPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212032   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212032(2-(2-methyl-1H-indol-5-ylamino)-4-phenylpyrimidine...)
Affinity DataIC50: 410nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212032(2-(2-methyl-1H-indol-5-ylamino)-4-phenylpyrimidine...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed