BDBM50212029 4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-morpholinoethyl)phenylamino)pyrimidine-5-carbonitrile::CHEMBL231800

SMILES CC(C)(N)c1ccc(cc1)-c1nc(Nc2ccc(CCN3CCOCC3)cc2)ncc1C#N

InChI Key InChIKey=MROGTPNQSHMKIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212029   

TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212029(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-morpholin...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212029(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-morpholin...)
Affinity DataIC50: 27nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed