BDBM50212026 4-(benzo[d]thiazol-2-yl)-2-(4-(2-hydroxyethyl)phenylamino)pyrimidine-5-carbonitrile::CHEMBL234489

SMILES OCCc1ccc(Nc2ncc(C#N)c(n2)-c2nc3ccccc3s2)cc1

InChI Key InChIKey=DPZDYVYBTGSQLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212026   

TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212026(4-(benzo[d]thiazol-2-yl)-2-(4-(2-hydroxyethyl)phen...)
Affinity DataIC50: 560nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212026(4-(benzo[d]thiazol-2-yl)-2-(4-(2-hydroxyethyl)phen...)
Affinity DataIC50: 340nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed