BDBM50212017 2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-5-yl)pyrimidine-5-carbonitrile::CHEMBL389102

SMILES OCCc1ccc(Nc2ncc(C#N)c(n2)-c2ccc3[nH]ccc3c2)cc1

InChI Key InChIKey=XNHXNJLWTFRLFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212017   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212017(2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-5-yl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212017(2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-5-yl...)
Affinity DataIC50: 410nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed