BDBM50212014 4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(2-ethyl-1H-imidazol-1-yl)ethyl)phenylamino)pyrimidine-5-carbonitrile::CHEMBL231824

SMILES CCc1nccn1CCc1ccc(Nc2ncc(C#N)c(n2)-c2ccc(cc2)C(C)(C)N)cc1

InChI Key InChIKey=MZMVWIRLRMOWQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212014   

TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212014(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(2-ethyl-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212014(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(2-ethyl-...)
Affinity DataIC50: 94nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed