BDBM50212013 2-(4-(2-hydroxyethyl)phenylamino)-4-(4-(2-hydroxypropan-2-yl)phenyl)pyrimidine-5-carbonitrile::CHEMBL234697

SMILES CC(C)(O)c1ccc(cc1)-c1nc(Nc2ccc(CCO)cc2)ncc1C#N

InChI Key InChIKey=GRRZCKUZPOCEPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212013   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212013(2-(4-(2-hydroxyethyl)phenylamino)-4-(4-(2-hydroxyp...)
Affinity DataIC50: 410nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212013(2-(4-(2-hydroxyethyl)phenylamino)-4-(4-(2-hydroxyp...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed