BDBM50211956 2-(3-hydroxy-5-methoxyphenethyl)phenol::Batatasin IV (5)::CHEMBL228126::US20240398793, Compound 9::batatasin IV

SMILES COc1cc(cc(c1)O)CCc2ccccc2O

InChI Key InChIKey=IUMFLNFLJUUODE-UHFFFAOYSA-N

Data  1 KI  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211956   

TargetProstaglandin G/H synthase 1(Human)
Chiang Mai University

Curated by ChEMBL
LigandPNGBDBM50211956(2-(3-hydroxy-5-methoxyphenethyl)phenol | batatasin...)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of COX1 by radioimmunoassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Chiang Mai University

Curated by ChEMBL
LigandPNGBDBM50211956(2-(3-hydroxy-5-methoxyphenethyl)phenol | batatasin...)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of COX2 by radioimmunoassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50211956(2-(3-hydroxy-5-methoxyphenethyl)phenol | batatasin...)
Affinity DataIC50: 4.09E+5nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50211956(2-(3-hydroxy-5-methoxyphenethyl)phenol | batatasin...)
Affinity DataIC50: 4.09E+5nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Celltaxis

US Patent
LigandPNGBDBM50211956(2-(3-hydroxy-5-methoxyphenethyl)phenol | batatasin...)
Affinity DataIC50: 500nMAssay Description:The hydrolase-homogeneous time resolved fluorescence assay is a two-step assay that measures the hydrolysis of LTA4 to LTB4 by analyzing the amount o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetPancreatic triacylglycerol lipase(Pig)
Seoul National University

LigandPNGBDBM50211956(2-(3-hydroxy-5-methoxyphenethyl)phenol | batatasin...)
Affinity DataKi:  6.28E+3nM ΔG°:  -7.38kcal/mole IC50: 3.01E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed