BDBM50211349 CHEMBL232592::N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2-nitrobenzenesulfonamide

SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@@H]1CC[C@@H](CC1)NS(=O)(=O)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=HEEKUWDLPPDKMK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211349   

TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211349(N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to human cloned adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211349(N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to human cloned adrenergic alpha-1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211349(N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  51nMAssay Description:Binding affinity to human dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211349(N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  201nMAssay Description:Binding affinity to human cloned adrenergic alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed