BDBM50211336 CHEMBL234422::N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2-methoxy-5-nitrobenzenesulfonamide

SMILES COc1ccc(cc1S(=O)(=O)N[C@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccc1OC(C)C)[N+]([O-])=O

InChI Key InChIKey=FFXLCCZAXLBJFW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211336   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211336(N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human cloned adrenergic alpha-1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211336(N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211336(N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  22nMAssay Description:Binding affinity to human cloned adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211336(N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl...)
Affinity DataKi:  173nMAssay Description:Binding affinity to human cloned adrenergic alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed