BDBM50211320 2-cyano-N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)benzenesulfonamide::CHEMBL234680

SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@H]1CC[C@@H](CC1)NS(=O)(=O)c1ccccc1C#N

InChI Key InChIKey=PAUUPYPPPJQSIG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211320   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211320(2-cyano-N-((1r,4r)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  0.770nMAssay Description:Binding affinity to human cloned adrenergic alpha-1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211320(2-cyano-N-((1r,4r)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to human dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211320(2-cyano-N-((1r,4r)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to human cloned adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211320(2-cyano-N-((1r,4r)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human cloned adrenergic alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed