BDBM50211042 CHEMBL388257::ethyl 4-(naphthalen-2-yl)-1,2,5,6-tetrahydropyridine-3-carboxylate

SMILES CCOC(=O)C1=C(CCNC1)c1ccc2ccccc2c1

InChI Key InChIKey=XYPXWICAIAFXBP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211042   

TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211042(ethyl 4-(naphthalen-2-yl)-1,2,5,6-tetrahydropyridi...)
Affinity DataKi:  79nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211042(ethyl 4-(naphthalen-2-yl)-1,2,5,6-tetrahydropyridi...)
Affinity DataKi:  268nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211042(ethyl 4-(naphthalen-2-yl)-1,2,5,6-tetrahydropyridi...)
Affinity DataKi:  440nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed