BDBM50211032 CHEMBL232671::methyl 2-(3-chlorophenyl)cyclopent-1-enecarboxylate

SMILES COC(=O)C1=C(CCC1)c1cccc(Cl)c1

InChI Key InChIKey=WLWFROPHDLATTA-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211032   

TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211032(methyl 2-(3-chlorophenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211032(methyl 2-(3-chlorophenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  3.40E+4nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211032(methyl 2-(3-chlorophenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  4.70E+5nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211032(methyl 2-(3-chlorophenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  2.24E+6nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211032(methyl 2-(3-chlorophenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  2.85E+5nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed