BDBM50211031 CHEMBL242920::methyl 3,4-trans-N-methyl-4-(4-iodophenyl)piperidine-3-carboxylate

SMILES COC(=O)[C@@H]1CN(C)CC[C@H]1c1ccc(I)cc1

InChI Key InChIKey=MXCAKGCIGZRYGJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211031   

TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211031(methyl 3,4-trans-N-methyl-4-(4-iodophenyl)piperidi...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211031(methyl 3,4-trans-N-methyl-4-(4-iodophenyl)piperidi...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211031(methyl 3,4-trans-N-methyl-4-(4-iodophenyl)piperidi...)
Affinity DataKi:  2.81E+3nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed