BDBM50211019 CHEMBL233088::methyl 2-(3,4-dichlorophenyl)cyclohept-1-enecarboxylate

SMILES COC(=O)C1=C(CCCCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JCGZOWXIYHYCOD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211019   

TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211019(methyl 2-(3,4-dichlorophenyl)cyclohept-1-enecarbox...)
Affinity DataKi:  515nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211019(methyl 2-(3,4-dichlorophenyl)cyclohept-1-enecarbox...)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211019(methyl 2-(3,4-dichlorophenyl)cyclohept-1-enecarbox...)
Affinity DataKi:  4.72E+3nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211019(methyl 2-(3,4-dichlorophenyl)cyclohept-1-enecarbox...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211019(methyl 2-(3,4-dichlorophenyl)cyclohept-1-enecarbox...)
Affinity DataKi:  1.49E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed