BDBM50211006 CHEMBL396082::methyl 2-(naphthalen-2-yl)cyclopent-1-enecarboxylate

SMILES COC(=O)C1=C(CCC1)c1ccc2ccccc2c1

InChI Key InChIKey=QGGSNXQBFWAFCC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211006   

TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211006(methyl 2-(naphthalen-2-yl)cyclopent-1-enecarboxyla...)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211006(methyl 2-(naphthalen-2-yl)cyclopent-1-enecarboxyla...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211006(methyl 2-(naphthalen-2-yl)cyclopent-1-enecarboxyla...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211006(methyl 2-(naphthalen-2-yl)cyclopent-1-enecarboxyla...)
Affinity DataKi:  3.90E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211006(methyl 2-(naphthalen-2-yl)cyclopent-1-enecarboxyla...)
Affinity DataKi:  4.17E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed