BDBM50210940 CHEMBL3948914

SMILES CC(C)c1ccc(C)c(NC(=O)Cn2c(Cc3c(Cl)cccc3Cl)nc3ccccc23)c1

InChI Key InChIKey=YBCXRVFOLDVBCP-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210940   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataIC50: 74nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataKd:  108nMAssay Description:Binding affinity to recombinant human TSPO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed