BDBM50210701 CHEMBL3957025

SMILES COc1cc2c(Nc3ccc(NC(=O)Nc4ccc(Cl)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=BTNOFGNEUZFLRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210701   

TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210701(CHEMBL3957025)
Affinity DataIC50: 528nMAssay Description:Inhibition of N-terminal GST-tagged human VEGFR-2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210701(CHEMBL3957025)
Affinity DataIC50: 17nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed