BDBM50210694 CHEMBL3975598

SMILES COC(=O)CNC(=O)c1ccc(Nc2ncnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)cc1

InChI Key InChIKey=AHWBQKARTYIOQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210694   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210694(CHEMBL3975598)
Affinity DataIC50: 611nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210694(CHEMBL3975598)
Affinity DataIC50: 275nMAssay Description:Inhibition of N-terminal GST-tagged human VEGFR-2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed