BDBM50210676 CHEMBL3895541

SMILES NC(=N)c1ccc(COc2ccc3cc(CC(NS(=O)(=O)c4ccccc4)C(O)=O)ccc3c2)cc1

InChI Key InChIKey=CRFYSEBCMFTHEP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210676   

TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 1.33E+3nMAssay Description:Displacement of fibrinogen from human platelet GP2b/GP3a receptor after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 2.77E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 840nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 2.29E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of thrombin-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 2.36E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of U46619-induced platelet aggregation preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed