BDBM50210651 (R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate::CHEMBL389600

SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F

InChI Key InChIKey=DHWNCDYJQCLUTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210651   

TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210651((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of DPP8 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210651((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of DPP9 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210651((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...)
Affinity DataIC50: 190nMAssay Description:Inhibition of DPP4 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed