BDBM50210648 (R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one::CHEMBL233474

SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccncc1)Cc1cc(F)ccc1F

InChI Key InChIKey=RFTUWARMIKWZIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210648   

TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210648((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210648((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4...)
Affinity DataIC50: 65nMAssay Description:Inhibition of DPP4 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210648((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of DPP8 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed