BDBM50210639 (R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::CHEMBL234448

SMILES C[C@@H]1CN(CCN1CC[C@H]1OCCc2cc(ccc12)C(N)=O)c1cccc2cc(F)ccc12

InChI Key InChIKey=BVWYBVKUPUODDY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210639   

TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210639((R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methyl...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]citalopram from human 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210639((R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methyl...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210639((R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methyl...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]GR-125743 from human 5HT1D expressed in LM(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210639((R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methyl...)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]GR-125743 from human 5HT1B expressed in LM(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210639((R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methyl...)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A expressed in LM(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed