BDBM50210628 CHEMBL3946861

SMILES CCSc1ncc(-c2cc([nH]c(=N)c2C#N)-c2ccc(Br)cc2)n1Cc1ccccc1

InChI Key InChIKey=ZPUHISLIAUSNQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210628   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50210628(CHEMBL3946861)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human PDE3A using fluorescein-labelled cAMP as substrate measured after 60 mins by IMAP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50210628(CHEMBL3946861)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE3A (484 to 1141 residues) expressed in Sf9 cells using cAMP as substrate after 60 mins by IM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed