BDBM50210551 2'-amino oxazole[5,4-b]-N-cyclopropylmethylmorphinan::CHEMBL390911

SMILES Nc1nc2cc3C[C@@H]4[C@@H]5CCCC[C@]5(CCN4CC4CC4)c3cc2o1

InChI Key InChIKey=IZIZYUAWSQWDRE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210551   

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210551(2'-amino oxazole[5,4-b]-N-cyclopropylmethylmorphin...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210551(2'-amino oxazole[5,4-b]-N-cyclopropylmethylmorphin...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210551(2'-amino oxazole[5,4-b]-N-cyclopropylmethylmorphin...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210551(2'-amino oxazole[5,4-b]-N-cyclopropylmethylmorphin...)
Affinity DataKi:  150nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed