BDBM50210389 1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4-ol::CHEMBL228964

SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC

InChI Key InChIKey=MEIKCNSXEAPYGM-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210389   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210389(1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...)
Affinity DataEC50:  117nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210389(1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...)
Affinity DataKi:  3nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210389(1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...)
Affinity DataKi:  306nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210389(1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...)
Affinity DataKi:  843nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210389(1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...)
Affinity DataKi:  1.82E+4nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed