BDBM50210387 1-(dio-tolylmethyl)-4-phenylpiperidin-4-ol::CHEMBL389665

SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1C

InChI Key InChIKey=MHYKPRJMOSXVFG-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210387   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210387(1-(dio-tolylmethyl)-4-phenylpiperidin-4-ol | CHEMB...)
Affinity DataEC50:  114nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210387(1-(dio-tolylmethyl)-4-phenylpiperidin-4-ol | CHEMB...)
Affinity DataKi:  4nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210387(1-(dio-tolylmethyl)-4-phenylpiperidin-4-ol | CHEMB...)
Affinity DataKi:  1.71E+3nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210387(1-(dio-tolylmethyl)-4-phenylpiperidin-4-ol | CHEMB...)
Affinity DataKi:  2.15E+3nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210387(1-(dio-tolylmethyl)-4-phenylpiperidin-4-ol | CHEMB...)
Affinity DataKi:  5.79E+3nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed