BDBM50210308 6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-2 -yl)-1,4-dihydroindeno[1,2-c]pyrazole::CHEMBL375890

SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(s3)C#CCOc3ccccc3)c2)CC1

InChI Key InChIKey=WYZQHQXTFISUNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210308   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210308(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 316nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210308(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 22nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed