BDBM50209877 2-(3-fluorobenzyloxy)-5-(6-methoxy-7-(2-methoxyethoxy)quinazolin-4-ylamino)cyclohexa-2,5-diene-1,4-dione::CHEMBL396472

SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccc(F)c4)=CC3=O)c2cc1OC

InChI Key InChIKey=FFURJOHMJXGVNU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209877   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209877(2-(3-fluorobenzyloxy)-5-(6-methoxy-7-(2-methoxyeth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209877(2-(3-fluorobenzyloxy)-5-(6-methoxy-7-(2-methoxyeth...)
Affinity DataIC50: 46.1nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209877(2-(3-fluorobenzyloxy)-5-(6-methoxy-7-(2-methoxyeth...)
Affinity DataIC50: 188nMAssay Description:Inhibition of human VEGFR2 in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209877(2-(3-fluorobenzyloxy)-5-(6-methoxy-7-(2-methoxyeth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed