BDBM50209814 (4-(3-(dimethylamino)-1-(4-(trifluoromethyl)phenoxy)propyl)phenyl)(4-isopropylpiperazin-1-yl)methanone::CHEMBL393071

SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(cc1)C(CCN(C)C)Oc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IVJLIFNDWFYVMA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209814   

TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209814((4-(3-(dimethylamino)-1-(4-(trifluoromethyl)phenox...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209814((4-(3-(dimethylamino)-1-(4-(trifluoromethyl)phenox...)
Affinity DataKi:  42nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209814((4-(3-(dimethylamino)-1-(4-(trifluoromethyl)phenox...)
Affinity DataKi:  44nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed