BDBM50209672 CHEMBL3884222

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3ccc(NC(C)=O)cc3NC(=O)C=C)n2)cc1

InChI Key InChIKey=JVAZQIMLEVDTDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209672   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209672(CHEMBL3884222)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of full length recombinant human His-tagged MEK1 expressed in baculovirus expression system after 1 hr by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209672(CHEMBL3884222)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of full length recombinant human GST-tagged TAK1 expressed in baculovirus expression system after 1 hr by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed