BDBM50209638 CHEMBL3883974

SMILES CC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCNC(=O)CCCCCSc1nc2ccccc2s1)NC(=O)[C@H](CCCCNC(C)=O)NC(C)=O)C(N)=O

InChI Key InChIKey=UNWOUMIQAOKAID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209638   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209638(CHEMBL3883974)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209638(CHEMBL3883974)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 (2 to 389 residues) expressed in Escherichia coli assessed as inhibition of H2N-HK-[epsilonN-acetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50209638(CHEMBL3883974)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 (101 to 399 residues) expressed in Escherichia coli assessed as inhibition of H2N-HK-[epsilonN-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed