BDBM50209401 1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione::CHEMBL242932

SMILES FC(F)(F)c1ccc(cc1)C(=O)C(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WHTKSZOXPDAVMH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209401   

TargetLiver carboxylesterase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50209401(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)
Affinity DataKi:  170nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCocaine esterase(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50209401(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)
Affinity DataKi:  180nMAssay Description:Inhibition of human intestinal carboxylesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50209401(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50209401(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed