BDBM50208940 5-bromo-pyridin-3-yl furan-2-carboxylate::5-bromopyridin-3-yl furan-2-carboxylate::CHEMBL222234::acs.jmedchem.1c00409_ST.37::jm5b01461, Compound 121

SMILES Brc1cncc(OC(=O)c2ccco2)c1

InChI Key InChIKey=HMICIXHTRIFAET-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50208940   

TargetReplicase polyprotein 1a(SARS-CoV)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50208940(5-bromopyridin-3-yl furan-2-carboxylate | 5-bromo-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of SARS coronavirus 3C-like proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HRV-16)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50208940(5-bromopyridin-3-yl furan-2-carboxylate | 5-bromo-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM50208940(5-bromopyridin-3-yl furan-2-carboxylate | 5-bromo-...)
Affinity DataIC50: 50nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM50208940(5-bromopyridin-3-yl furan-2-carboxylate | 5-bromo-...)
Affinity DataIC50: 50nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed