BDBM50208825 (+)-3,4,3',4'-tetrahydroxy-9,7'alpha-epoxylignano-7 alpha,9'-lactone::CHEMBL227135

SMILES Oc1ccc(cc1O)[C@H]1OC(=O)[C@H]2[C@@H]1CO[C@@H]2c1ccc(O)c(O)c1

InChI Key InChIKey=DFZNKMAEHVZMHR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208825   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Tahitian Noni International

Curated by ChEMBL
LigandPNGBDBM50208825((+)-3,4,3',4'-tetrahydroxy-9,7'alpha-epoxylignano-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of 5LOX in human PBMC by EIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Tahitian Noni International

Curated by ChEMBL
LigandPNGBDBM50208825((+)-3,4,3',4'-tetrahydroxy-9,7'alpha-epoxylignano-...)
Affinity DataIC50: 520nMAssay Description:Inhibition of 15LOX in rabbit reticulocytes by EIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tahitian Noni International

Curated by ChEMBL
LigandPNGBDBM50208825((+)-3,4,3',4'-tetrahydroxy-9,7'alpha-epoxylignano-...)
Affinity DataIC50: 9.02E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect Sf21 cells by EIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed