BDBM50208822 (-)-3,3'-bisdemethylpinoresinol::CHEMBL227187

SMILES Oc1ccc(cc1O)[C@@H]1OC[C@@H]2[C@H]1CO[C@H]2c1ccc(O)c(O)c1

InChI Key InChIKey=OQSOTSIYXPYTRE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50208822   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Tahitian Noni International

Curated by ChEMBL
LigandPNGBDBM50208822((-)-3,3'-bisdemethylpinoresinol | CHEMBL227187)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of 5LOX in human PBMC by EIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tahitian Noni International

Curated by ChEMBL
LigandPNGBDBM50208822((-)-3,3'-bisdemethylpinoresinol | CHEMBL227187)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX2 expressed in insect Sf21 cells by EIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Tahitian Noni International

Curated by ChEMBL
LigandPNGBDBM50208822((-)-3,3'-bisdemethylpinoresinol | CHEMBL227187)
Affinity DataIC50: 520nMAssay Description:Inhibition of 15LOX in rabbit reticulocytes by EIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50208822((-)-3,3'-bisdemethylpinoresinol | CHEMBL227187)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as p-nitrophenol release from pNPP substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed