BDBM50208721 4-(biphenyl-3-yl)-5-(piperidin-4-yl)isoxazol-3-ol::CHEMBL1204123::CHEMBL223324

SMILES O=c1[nH]oc(C2CCNCC2)c1-c1cccc(c1)-c1ccccc1

InChI Key InChIKey=KLKHVLINJXRNBG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208721   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50208721(CHEMBL1204123 | CHEMBL223324 | 4-(biphenyl-3-yl)-5...)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50208721(CHEMBL1204123 | CHEMBL223324 | 4-(biphenyl-3-yl)-5...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed