BDBM50208647 (R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-phenyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-2-amino-2-methylpropanamide::CHEMBL374757

SMILES CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1-c1ccccc1

InChI Key InChIKey=JIARPYFXIWDCPV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208647   

TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208647((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-phenyl-4H-1...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I-His9]ghrelin from human GHS1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208647((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-phenyl-4H-1...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed