BDBM50208636 CHEMBL3884932

SMILES COc1ccc2[nH]c3c(c(cc4cncc(OC)c34)C#N)c2c1

InChI Key InChIKey=VTDMTVMKVZXVSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208636   

TargetDual specificity protein kinase CLK1(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208636(CHEMBL3884932)
Affinity DataIC50: 56nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208636(CHEMBL3884932)
Affinity DataIC50: 600nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208636(CHEMBL3884932)
Affinity DataIC50: 930nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed