BDBM50208412 2-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methylamino)ethanol::CHEMBL391321

SMILES OCCNCc1ccn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12

InChI Key InChIKey=OYULNTIUXDXAGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208412   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208412(2-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyr...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208412(2-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyr...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed