BDBM50208408 CHEMBL400413::N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-(methylsulfonyl)-1,4-diazepan-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

SMILES CS(=O)(=O)N1CCCN(Cc2ccn3ncnc(Nc4ccc5n(Cc6cccc(F)c6)ncc5c4)c23)CC1

InChI Key InChIKey=XHEGSRSQWOQKMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208408   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208408(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-(meth...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208408(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-(meth...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed