BDBM50208407 CHEMBL232082::N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-methylpiperazin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

SMILES CN1CCN(Cc2ccn3ncnc(Nc4ccc5n(Cc6cccc(F)c6)ncc5c4)c23)CC1

InChI Key InChIKey=DQYLUXJFGRYNJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208407   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208407(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-methy...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208407(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-methy...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed