BDBM50208405 CHEMBL391675::N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

SMILES Fc1cccc(Cn2ncc3cc(Nc4ncnn5ccc(CN6CCCC6)c45)ccc23)c1

InChI Key InChIKey=PDXYGSYLHJULFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208405   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208405(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-(pyrrolid...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208405(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-(pyrrolid...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed