BDBM50208218 CHEMBL3883432

SMILES O=S(=O)(c1ccccc1)n1ccc2c(cccc12)N1CCN(CCCCCCCCNc2c3CCCCc3nc3ccccc23)CC1

InChI Key InChIKey=FZNAHZCVWVQRSJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50208218   

TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208218(CHEMBL3883432)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of electric eel AChE preincubated for 5 mins followed by acetylthiocholine iodide substrate addition measured after 5 mins by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2018
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208218(CHEMBL3883432)
Affinity DataIC50: 12nMAssay Description:Inhibition of equine serum BuChE preincubated for 5 mins followed by butyrylthiocholine iodide substrate addition measured after 5 mins by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208218(CHEMBL3883432)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant AChE preincubated for 5 mins followed by acetylthiocholine iodide substrate addition measured after 5 mins by Ellman'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208218(CHEMBL3883432)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in CHOK1 cell membranes measured after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2018
Entry Details Article
PubMed