BDBM50208176 CHEMBL3976777

SMILES Nc1ncnc(N2CCC[C@H]2c2nn3cccc3c(=O)n2-c2ccccc2)c1C#N

InChI Key InChIKey=QOGPJIWCEKLLOE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208176   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50208176(CHEMBL3976777)Copy SMILESCopy InChI

Affinity DataIC50: 4.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/30/2018
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50208176(CHEMBL3976777)Copy SMILESCopy InChI

Affinity DataIC50: 6.60nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/30/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL