BDBM50208007 3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fluorophenyl)-imidazolidin-2-one::CHEMBL223079

SMILES Fc1ccc(cc1)C1(CN(C2CCN(Cc3cccc(Cl)c3)CC2)C(=O)N1)c1ccc(F)cc1

InChI Key InChIKey=PPZQHODYVASSTK-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208007   

TargetCytochrome P450 2C19(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208007(3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human CYP2C19 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208007(3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208007(3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human CYP2D6 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208007(3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208007(3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human CYP2C9 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208007(3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human muscarinic M3 receptor expressed in CHO K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208007(3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataKi:  955nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human muscarinic M2 receptor expressed in CHO K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed